preliminary data suggest possible association between il-32 expression level and time of ms attack

il-32 and tnf? are important cytokines in autoimmune and inflammatory diseases. il-32 has not been previously studied with respect to ms. here, we report il-32 and tnf? transcript levels in peripheral blood mononuclear cells of ms patients and control individuals by real time pcr. a significant difference in il-32 and tnf? mrna levels of patients as compared to controls was not observed. however, patients with more recent attacks had highly significant increased levels of il-32 mrnas. as the sample size was small, this potentially relevant preliminary observation needs to be corroborated using a larger number of patients with well defined clinical features..? 2011 progress in biological sciences. vol. 1, no. 2, 44-49.